It's On (Dr. Dre) 187um Killa is the second EP released by American rapper Eazy-E and the last project to be released during his lifetime. It was released on October 19, 1993 via Relativity Records and Eazy-E's Ruthless Records, as a response to Dr. Dre's debut solo album The Chronic, which repeatedly attacks Eazy.

To follow up his 1992 EP 5150: Home 4 tha Sick, Eazy-E had planned a double album named Temporary Insanity. Yet to exploit Dre's spotlight and his May 1993 single "Fuck wit Dre Day", which mainly disses him, Eazy changed plans. On this EP, shots at Dre are absent from only three tracks: "Gimmie That Nutt", "Any Last Werdz", and "Boyz-N-the-Hood (G-Mix)". The lead single, "Real Muthaphuckkin G's"—which, alike "Any Last Werdz", carried a music video—became Eazy's most successful single.