Sublime with Rome is a band that began as a musical collaboration between former Sublime members Eric Wilson and Bud Gaugh, and singer and guitarist Rome Ramirez. The group's name was not only a reference to the singer's first name, but to the fact that they chiefly performed songs by the original Sublime, which was fronted by Bradley Nowell until his death in 1996.

Ramirez began performing with Gaugh and Wilson in 2009, where they played under the name "Sublime", until Nowell's estate issued a legal challenge to the use of the trademarked name for a venture not including Nowell. As a result, they changed their name to "Sublime with Rome" in January 2010. The group played at the 2009 Smokeout Festival and embarked on their first tour in 2010, before releasing their debut album, Yours Truly, on July 12, 2011. Gaugh left the band on December 10, 2011, and was replaced by Josh Freese. The lineup of Wilson, Ramirez and Freese recorded the group's second album Sirens, which was released in 2015. Sublime with Rome's third lineup change took place in 2017, when Carlos Verdugo replaced Freese.

In May 2019, the new trio released their first album together, and the third for Sublime With Rome, titled Blessings. The album, produced by Rob Cavallo, features the song "Wicked Heart" as the album's first single, reaching No. 34 on Billboard's Alternative Songs chart.

In 2023, Verdugo left the lineup and was briefly replaced by drummer Jason Vick before Joe Tomino of Dub Trio took over on drums just before the November release of the band's Tangerine Skies EP. A little over a month after the EP's release, Ramirez announced that he would be departing the band at the end of 2024 and moving on to focus on his solo career. On February 26, 2024, Eric Wilson announced that he was no longer a member of Sublime with Rome. In March 2024, the band officially announced its farewell tour dates.