S'Express (pronounced ess-express; sometimes spelled S'Xpress or S-Express) was a British dance music act from the late 1980s, who had one of the earliest commercial successes in the acid house genre.

"Theme from S'Express", which contained elements from Rose Royce's "Is It Love You're After", was one of the earliest recordings to capitalize on the emergence of sampling culture. The song went to number one in the UK Singles Chart for two weeks in April 1988. It made the Hot Dance Club Play chart in the US (also scraping into the U.S. Billboard Hot 100 at number 91). In 2016 Mark Moore released a remix album called Enjoy This Trip which retooled S’Express’s music for the 21st century through working with guests such as Punks Jump Up and Chris & Cosey.