Jamie Saft is an American keyboardist and multi-instrumentalist and composer. He was born in New York City and raised a Conservative Jew, and studied at Tufts University and the New England Conservatory of Music.

Saft moved from Brooklyn to the Hudson Valley around 2007, and lived near Roswell Rudd. The two often played together, and Rudd passed on knowledge of some of his own music and that of Herbie Nichols.

He has performed and recorded with an eclectic variety of artists including John Zorn, Wadada Leo Smith, Iggy Pop, Steve Swallow, Bobby Previte, and Marc Ribot. He has also written several original film scores including Murderball and God Grew Tired of Us; selections from these were released by Tzadik Records as A Bag of Shells. The same label has released several of Saft's recordings.