Palo Santo is the second studio album by the English electronic trio Years & Years, released by Polydor Records on 6 July 2018. Executive produced by the band, it is the follow-up to their debut album Communion (2015). After the success of their Communion, the trio felt pressured in making their sophomore record. Influenced by religion and spirituality, lead singer and principal songwriter Olly Alexander wanted to connect religious transcendence to pop music after perceiving parallels between a church's sense of belonging and gay nightclubs. The trio met with frequent and new collaborators such as Mark Ralph, Greg Kurstin, Steve Mac and Jesse Shatkin to produce most its tracks. Named after the South American "palo santo" (Spanish for "holy wood"), which was commonly used to fend off bad spirits, though Alexander used its name as a dick joke referring to men he knew, it is the group's last album as a trio.

Palo Santo is a concept album, set in the titular fictional world, where traditional rules regarding gender and sexuality are nonexistent. Its lyrical content deals with "the murky, complicated side" of desire, as well as the connection between religion and carnality, using religious iconography in dealing with themes of sexuality, queerness and guilt. Its visual imagery took inspirations from science fiction and technology where androids yearn to experience emotion. Sonically, the album is a dance-pop and electropop record influenced by 1990s pop and R&B music. Palo Santo's release was accompanied by a short film of the same name. Its promotional campaign features a single aesthetic of a dystopian future in Palo Santo, both of which were prominently used for the album and its accompanying film.

Upon its release, Palo Santo received widespread praise from music critics, some of whom lauded its deeper emotional resonance compared to its predecessor, Alexander's refusal to embrace moral didacticism and his vibrant display of character. Commercially, the album debuted at number three the UK Albums Chart and became the band's second album to top the Billboard Dance/Electronic Albums chart. Five singles were released from the album: "Sanctify", "If You're Over Me", "All for You", "Play" and "Valentino with "Sanctify", "If You're Over Me" and "Play" making the top forty on the UK Singles Chart, and "If You're Over Me" and "Play" became top ten hits. The trio supported the album with the Palo Santo Tour, which commenced in October 2018 in North America and ended in June 2019 in England.